Clonal cell lines derived from BTI-TN-5B1-4
Patent No. 7,179,648
Issued: February 20, 2007
Inventors: Granados; Robert R. (Ithaca, NY), Li; Guoxun (Qingdao, CN)
Improved insect cell lines, two of which are designated H5CL-B and H5CL-F (both of which are derived from the parental cell line BTI-TN-5B1-4, ATCC CRL 10859), possess the properties of increased production of baculovirus particles, increased expression of foreign proteins using a baculovirus expression system, and increased resistance to cell culture stress, relative to the parental cell line.
REFERENCE TO RELATED APPLICATIONS
This application claims an invention which was disclosed in Provisional Application No. 60/426,535, filed Nov. 15, 2002, entitled "IMPROVED CLONAL CELL LINES DERIVED FROM BTI-TN-5B1-4". The benefit under 35 USC .sctn. 119(e) of the United States provisional application is hereby claimed, and the aforementioned application is hereby incorporated herein by reference in its entirety.
For more cell line patents from Boyce Thompson Institute, see:
6,858,205 GP64-null baculoviruses pseudotyped with heterologous envelope proteins for gene therapy - from Boyce Thompson Institute for Plant Reseach
6,770,799 Expression of recombinant human acetylcholinesterase in transgenic plants - a transgenic plant that is capable of expressing a physiologically active human acetylcholinesterase
6,765,127 Invertebrate intestinal mucin cDNA and related products and methods - an insect intestinal mucin protein derived from Tricoplusia ni, useful for production of transgenic cells having insecticidal activity
5,962,765 Molecular cloning of a complimentary DNA sequence encoding a cuticle degrading protease produced by entomopathogenic fungi .
5,750,383 Baculovirus Cloning System - a marker-rescue system using an essential gene
5,593,669 and 6,090,379 Stable Pre-Occluded Virus Particle - A method of infecting insects using a baculovirus, including use as an insecticide.
Go Back for more representative patents.
Home || Intellectual Property || Patents || Trademarks || Copyrights
Brown & Michaels, PC
400 M & T Bank Building
118 North Tioga Street - The Commons
Ithaca, NY 14850
Phone: (607) 256-2000 · Fax: (607) 256-3628
© 2007 Brown & Michaels PC