Patent number: 8961951
Baculoviruses with enhanced virion production and a method for the production of baculoviruses
Original Assignee: Boyce Thompson Institute for Plant Research, Inc.
Field of technology: Biotech
Patent granted on: Tue, 24 Feb 2015
Abstract
The present invention provides a method for restoring budding capability to GP64null baculoviruses including gp64null AcMNPV by expressing therein a portion of the VSV G protein gene or a truncated “stem” portion of the GP64 gene. Other embodiments provide methods to use portions of the G-stem or GP64 protein to target foreign proteins for display on virions.