Patent number: 9980941

Quaternary ammonium anti-cholinergic muscarinic receptor antagonists

Inventors:

  • Rich; Steven A.

Field of technology: Biotech, Medical

Patent granted on: Tue, 29 May 2018

Patent drawing

Abstract

A method administers quaternary ammonium anti-cholinergic muscarinic receptor antagonists in combination with acetyl-cholinesterase inhibitors to treat either cognitive impairment or acute delirium. This therapy results in a modification of a cognitive disorder or disease, namely a slow down in the disease progression. In one preferred embodiment, the disease is dementia with Lewy Bodies. New formulations for quaternary ammonium anti-cholinergic muscarinic receptor antagonists are also disclosed.